Quinupristin/dalfopristin: therapeutic potential for vancomycin-resistant enterococcal infections

Quinupristin/dalfopristin: therapeutic potential for vancomycin-resistant enterococcal infections.

Vancomycin-resistant Enterococcus faecium (VREF) is an opportunistic pathogen, which causes infections among severely ill, hospitalized patients, in whom it is likely to increase the risk of progressive local or systemic disease and to worsen the prognosis. Because these organisms are often highly resistant to penicillin, ampicillin and many other antimicrobials including the glycopeptides, the...

Daptomycin for the treatment of vancomycin-resistant enterococcal infections.

Vancomycin-resistant enterococcal endophthalmitis.

V ancomycin-sensitive enterococcal acute endophthalmitis has been reported following cataract extraction, penetrating keratoplasty, trabeculectomy, and pupilloplasty. However, vancomycinresistant enterococcal (VRE) endophthalmitis has been described in only 3 patients to date: an immunocompromised, hospitalized patient with underlying bacteremia, an immunocompetent patient following keratoplast...

Vancomycin-resistant enterococcal infections: epidemiology, clinical manifestations, and optimal management

Since its discovery in England and France in 1986, vancomycin-resistant Enterococcus has increasingly become a major nosocomial pathogen worldwide. Enterococci are prolific colonizers, with tremendous genome plasticity and a propensity for persistence in hospital environments, allowing for increased transmission and the dissemination of resistance elements. Infections typically present in immun...

Resistant Nosocomial Enterococcal Infections

Enterococcus faecalis, formerly classified as Streptococcus faecalis, belongs to Lancefield group D and is frequently isolated from nosocomial infections. Of the nosocomial infections reported to the Centers for Disease Control (CDC) in its National Nosocomial Infection Survey (NNIS), enterococci were isolated from 11% of cases. Frequently, E. faecalis is recovered as one of several kinds of ba...